Unity Analytics has introduced Remote Settings to enable Unity Developers to update games on-the-fly. It's native to Unity and employs an API similar to PlayerPrefs.
This is very promising because published games can be tweaked and modified without jumping through many hurdles. The package can be downloaded here.
Source: https://blogs.unity3d.com/2017/06/02/introducing-remote-settings-update-your-game-in-an-instant/